Noorduin Lab

Research focus

ERC Consolidator Grant · 2021

Crystals of single chirality via non-equilibrium routes

The molecular building blocks of life are of only one handedness. Consequently, pharmaceuticals and other bioactive molecules also need to be of one handedness. When such enantiomers crystallize in separate crystals, isolation of the desired handedness is relatively straightforward. Unfortunately, most enantiomers (90-95%) are thermodynamically more stable as racemic compounds with both enantiomers in the crystallographic unit cell, which impedes any such separations. There are currently no methods to systematically overcome this major bottleneck, thus hindering simple routes towards many essential enantiopure molecules. This proposal is aimed at overcoming this fundamental challenge by…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.