ERC Starting Grant · 2021
Energy transduction in KInetically asymmetric catalytic NETworks
Endergonic processes are central to Life. They are achieved by enzymes, that change conformation during their catalytic cycle. Thus, biological non-equilibrium processes are catalysis-driven. The realization of catalysis-driven processes in artificial systems proved challenging. It remains limited to synthetically demanding interlocked structures, which were upgraded with catalytic features affecting ring sliding motion. With KI-NET, I want to develop a general biomimetic strategy enabling endergonic processes driven by chemical catalysis. I plan to invert the current approach by introducing defined conformational freedom into simple catalytic units. KI-NET scientific objectives go beyond…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.
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