Heuke Lab

National Centre for Scientific Research (CNRS)

Ile-de-France (FR1) · France

ERC-funded
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ERC Consolidator Grant · 2023

Backscattering coherent Stokes Raman scattering (sCiSsoRS) for real-time cancer diagnostics

The gold-standard for cancer diagnosis is the pathological examination of Hematoxylin & Eosin (HE) stained tissue. Though well adopted worldwide for the coloration of large numbers of cancer sections, the classical HE-staining procedure is unable to provide a fast-feedback to surgeons within less than 30min. This latency compromises the efficiency and accuracy of any tumor resection with numerous negative impacts for the success of the surgery and patient’s health prospect. Recently, the chemical-bond-specific image contrast provided by stimulated Raman scattering (SRS) was shown to be suitable for the generation of HE-like images. However, the SRS signal fundamentally propagates forward…

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