ERC Advanced Grant · 2024
Nanoscale Analysis of Inter-Organelle Interactions and their Role in Neuronal Plasticity
Cellular communication is mediated by nanometer-sized organelles (vesicles, stress granules, exosomes) that are potentially responsible for carrying and releasing signalling molecules. I propose to use my extensive background in electroanalytical chemistry and mass spectrometry imaging to develop new technologies to chemically dissect vesicles, exosomes, and stress granules both dynamically and in fixed samples with spatial discrimination across living cells - the next frontier in cell analysis. The following four aims are proposed. I will develop 1) methods to chemically dissect and dynamically determine chemical species at and in nanometer organelles and suborganelles, 2) methods to…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.