Kurzbach Lab

University of Vienna

Ostösterreich (AT1) · Austria

ERC-funded
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ERC Consolidator Grant · 2025

Hyperpolarized Surface-enhanced Liquid-State Spectroscopy

Across science, medicine, and industry, nuclear magnetic resonance (NMR) is a key technique with the unique capacity to provide atomistically detailed molecular models. Its primary drawback, however, lies in its low sensitivity, limiting its ability to address critical scientific questions. A potential answer is hyperpolarization via dissolution dynamic nuclear polarization (dDNP), which can amplify NMR sensitivity 10,000-fold. Despite this promise, dDNP remains a niche method constrained to a narrow range of substrates. Most experiments and nearly all biomolecules remain beyond dDNP’s reach; thus, a plethora of opportunities are missed. HypSurf aims to exploit the full potential of dDNP by…

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