ERC Advanced Grant · 2017
Can we reconstruct in the lab the onset of molecular evolution? To trigger the autonomous emergence of the first oligonucleotide sequences, we will explore non-equilibrium boundary conditions and selective mechanisms to host the fast progressing prebiotic replication chemistry of oligonucleotides. We will explore novel water-fog microfluidic settings to boost the replication and selection of the first RNA sequences. The findings aims to enable the creation of primitive life forms in the lab, starting from simple molecules in heated rock pores of early Earth. Autonomous replication and metabolism. We will expand our thermal gradient expertise to host three replication chemistries. Using 3D…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.