Prevedel Lab

European Molecular Biology Laboratory (EMBL)

Baden-Württemberg (DE1) · Germany

ERC-funded
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Research focus

ERC Consolidator Grant · 2019

Development of advanced optical tools for studying cellular mechanics at high spatial and temporal resolution

A long-standing aim in the life sciences is to understand development and morphogenesis, i.e. how organismal shape is encoded by the genome and how cellular mechanics are involved in its execution. Lately, investigations have started to focus on the mechanical properties of the involved multicellular compartments, and the interwoven mechanical - molecular interactions at the cellular scale. While molecular components can routinely be visualized with fluorescence microscopy, assessing the mechanical properties of living cells with similar spatio-temporal resolution in a non-invasive fashion has long been an open challenge. Recently, a new type of optical elastography, namely Brillouin…

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