ERC Advanced Grant · 2022
The geometrical and physical basis of cell-like functionality
Can systems with life-like properties be built from scratch with only a minimal set of components? While progress has been made experimentally in the development of such minimal systems, there is a lack of theoretical underpinnings that could provide mechanistic principles. My goal is to discover such principles by combining theoretical modeling and in-silico evolution to explore the potential for life-like functions of minimal systems consisting of only two core elements of cells: reaction compartments enclosed by lipid membranes (liposomes) and equipped with a protein reaction network. Towards this goal, we will develop new multi-scale approaches to investigate the mechanistic interplay…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.