Shi Lab

University of Leuven

Vlaams Gewest (BE2) · Belgium

ERC-funded
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ERC Starting Grant · 2024

Bioinspired Transmembrane Nanomachines

A hallmark of life is its ability to utilise local free energy to do work at molecular scales. Such work is done by millions of sophisticated protein complexes that act as nanomachines. Prominent among these are the transmembrane motor proteins. They lie at the centre of life-critical molecular processes such as ATP synthase and bacterial propulsion. Despite the great attention creating artificial molecular machines has received across scientific disciplines, constructing artificial transmembrane nanomachines remains largely unexplored. Such transmembrane artificial nanomachines would give us direct access to one of life’s most universal energy sources, transmembrane electrochemical…

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