ERC Starting Grant · 2025
Beyond a snapshot: Spatiotemporal Multiomics for the study of Breast Cancer phenotypic transitions
This proposal aims to address a critical knowledge gap in understanding phenotypic transitions in the context of chemotherapy resistance. Phenotypic transitions encompass various mechanisms that modify cellular phenotypes over time, including differentiation and metabolic reprogramming, among others. As some cellular phenotypes are transient and chemoresistant cells constitute a rare subpopulation, studying these important phenomena is challenging even with modern, high dimensional phenotyping methods (e.g. proteomics and transcriptomics), as they are intrinsically destructive for the sample and can only provide a single snapshot of these fleeting cellular states. To overcome this…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.
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