ERC Advanced Grant · 2021
Restoring anisotropy in living tissues 'in situ'
Regenerative Medicine aims to restore the composition and organisation of damaged tissues of the human body to regain tissue functionality. When regenerating tissues inside the body (in situ), however, restoration of tissue structural organisation is commonly overlooked. This is particularly problematic for the heart, where functional performance is inseparable from its structurally aligned (= anisotropic) organisation at length scales from the cell to the organ. Two decades of cell-, gene- and material-based therapies to regenerate the damaged heart have mainly targeted the restoration of tissue composition, so far with limited success. I hypothesise that synergistic restoration of tissue…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.