Laporte Lab

DWI – Leibniz Institute for Interactive Materials

Nordrhein-Westfalen (DEA) · Germany

ERC-funded
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ERC Consolidator Grant · 2021

3D-assembly of interactive microgels to grow in vitro vascularized, structured, and beating human cardiac tissues in high-throughput

Generating 3D in vitro functional tissues and organs in the millimeter scale remains an unmet dream of modern medicine. Irrespective of great efforts in the field of tissue engineering to design injectable/pipettable hydrogels or implantable/non-pipettable scaffolds for 3D cell growth, it is not yet possible to generate functional and personalized tissues with native-like structures and mature blood vessels. The main reason for this limitation is that current materials do not recapitulate the complexity and dynamics of the native cell environment. To create personalized human tissues, patient-derived induced pluripotent stem cells can differentiate in any cell type but controlling stem cell…

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