ERC Consolidator Grant · 2023
Cancer dormancy and the trigger to transition to active metastatic growth is a big open question. Current in vivo models focus on niche-specific cell and molecular mechanisms, ignoring biophysical aspects. Dormancy evolves with complex spatio-temporal dynamics; yet, there is a knowledge gap in the understanding of the heterogeneity of the units, and the dynamics of their interaction and evolution. Emergence occurs when a critical mass of units synergistically communicates giving rise to a new macro-level organization, with properties greater than the sum of the units. Engineering emergent phenomena in biological systems is a big research challenge as they originate from multiscale…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.