ERC Starting Grant · 2023
It is estimated that up to 90% of cancer deaths are caused not by the primary cancer but after it has metastasised, i.e. spread to other organs in the body, and it is well known that the locations of metastasised tumours are specific to the location of the primary cancer. Communication and transfer of material between cells is a fundamental process in cell biology, for which nature uses extracellular vesicles (EVs). These nanometre-sized vesicles are excreted by cells and contain signature combinations of membrane lipids, nucleic acids, proteins and surface markers. EVs excreted by cancer cells play an important role in communication between tumours and distant organs where metastases can…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.