Cidonio Lab

Sapienza University of Rome

Centro (IT) (ITI) · Italy

ERC-funded
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ERC Starting Grant · 2025

Bioprinting with Real-time Imaging and cell-biomaterial Density for Growth Enhancement

BRIDGE (Bioprinting with Real-time Imaging and cell-biomaterial Density for Growth Enhancement) wants to elevate 3D bioprinting with an unprecedented microfluidic-assisted approach for developing human skeletal tissue models, addressing gaps in control of the biofabrication deposition process, specifically cell-biomaterial density generation. Human tissues, such as bones, rely on graded cellular arrangements for physiological functions, yet mechanisms like mineralisation remain unclear due to inadequate models. Current 3D bioprinting techniques, typically dispense cells and materials at predefined single densities, but fail to replicate hierarchical, multicellular tissues, significantly…

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