Quarteroni Lab

Polytechnic University of Milan

Nord-Ovest (ITC) · Italy

ERC-funded
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ERC Advanced Grant · 2016

An Integrated Heart Model for the simulation of the cardiac function

The goal of this project is to construct, mathematically analyze, numerically approximate, computationally solve, and validate on clinically relevant cases a mathematically-based integrated heart model (IHM) for the human cardiac function. The IHM comprises several core cardiac models – electrophysiology, solid and fluid mechanics, microscopic cellular force generation, and valve dynamics – which are then coupled and finally embedded into the systemic and pulmonary blood circulations. It is a multiscale system of Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) featuring multiphysics interactions among the core models. The physical and mathematical properties…

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