Faulkner Lab

John Innes Centre - UK

- · United Kingdom

ERC-funded
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ERC Consolidator Grant · 2016

The role of the symplast in host-pathogen interactions – how does the symplastic, intercellular exchange of molecules regulate the outcomes of defence and infection?

Cell-to-cell communication is fundamental to multicellular organisms. The exchange of information and resources between cells and tissues enables co-ordination of responses to environmental and developmental signals. In plants, the cytoplasm of adjacent cells is connected by plasma membrane-line pores called plasmodesmata (PD) that cross the cell wall, generating cytoplasmic continuity between cells and tissues. This interconnected cytoplasm is termed the symplast and is unique to plants. In plants, growing evidence suggests that innate immune responses rely on regulation of symplastic connectivity. My group previously discovered that regulation of PD (whether they are open or closed) is…

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