Maglia Lab

University of Groningen

Noord-Nederland (NL1) · Netherlands

ERC-funded
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ERC Consolidator Grant · 2016

Design and Engineering Next-Generation Nanopore Devices for Bioplymer Analysis

Nanopores have emerged in the past few years as a promising analytical technique. The basic concept of nanopore sensing is to apply a potential across individual nanoscale pores and observe the disruption of the ionic flow caused by single molecules entering the pore. Ionic currents through protein pores have been successful at recognizing tiny differences in molecules in solution. Most notably, arrays of thousands of nanopores integrated in low-cost and portable devices are now capable of sequencing DNA at the single-molecule level. The main challenge of nanopore sensing is the inability of controlling the protein pore diameter and geometry, which determines the signal and enables…

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