ERC Starting Grant · 2016
Computational Design of Novel Functional Proteins for Immunoengineering
Finely orchestrated protein activities are at the heart of the most fundamental cellular processes. The rational and structure-based design of novel functional proteins holds the promise to revolutionize many important aspects in biology, medicine and biotechnology. Computational protein design has led the way on rational protein engineering, however many of these designed proteins were solely focused on structural accuracy and completely impaired of function. DeNovoImmunoDesign proposes novel computational design strategies centered on the exploration of de novo protein topologies and the use of structural flexibility with the ultimate goal of designing functional proteins. The proposed…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.
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