ERC Advanced Grant · 2017
Do Pathogen Extracellular Vesicles Deliver Crop Disease?
Filamentous plant pathogens (fungi and oomycetes) cause the most devastating crop diseases and thus significantly threaten global food security. Essential components of their virulence arsenal are proteins called cytoplasmic effectors that are delivered inside plant cells to suppress immunity. One of the major scientific challenges in this field is understanding how effectors are secreted and translocated into host cells; a question that is hotly debated. An exciting breakthrough in my laboratory revealed that cytoplasmic effectors accumulate in extracellular vesicles (EVs), implicating this as a delivery route. This critical discovery establishes a vital need to address: • What proteins…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.