ERC Starting Grant · 2017
Impact and interaction of prophage elements in bacterial host strains of biotechnological relevance
Phages, viruses that prey on bacteria, are the most abundant and diverse inhabitants of the Earth. Temperate bacteriophages are able to integrate into the host genome and maintain as prophages a long-term association with their host. Illustrated by the development of mutually beneficial traits, this close interaction between host and virus has significantly shaped bacterial evolution. However, the immense genetic resources of phage genomes still remain almost unexplored. For the transition to a sustainable bioeconomy, we strongly depend on microbes as hosts for the production of value-added compounds. PRO_PHAGE will exploit recent advances in next-generation sequencing (NGS), single-cell…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.