Santos Lab

New University of Lisbon

Este (ES5) · Portugal

ERC-funded
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ERC Starting Grant · 2018

Zooming the link between diet and brain health: how phenolic metabolites modulate brain inflammation

Currently a big concern of our aging society is to efficiently delay the onset of neurodegenerative diseases which are progressively rising in incidence. The paradigm that a diet rich in the phenolics, prevalent e.g. in fruits, is beneficial to brain health has reached the public. However their mechanistic actions in brain functions remain to be seen, particularly since the nature of those acting in the brain remains overlooked. I wish to address this gap by identifying candidate compounds that can support development of effective strategies to delay neurodegeneration. Specifically, I will be analysing the potential of dietary phenolics in both prevention and treatment (i.e delay) of…

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