ERC Starting Grant · 2019
A platform for rapidly mapping the molecular and systemic dynamics of aging
A central goal of molecular medicine is to understand how genetics, diet, and environment interact to determine health. However, most complex diseases arise from slow, stochastic changes involving large numbers of genes, making it difficult to systematically develop preventative therapies. To study the early and mid-life origins of late-life diseases, we need new methods capable of measuring the high-dimensional dynamics of physiologic change during aging. C. elegans is a small, fast-aging animal and a powerful model for asking fundamental questions about the conserved molecular origins of complex diseases. However, it is not yet feasible to systematically collect molecular and phenotypic…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.