Stiel Lab

Research focus

ERC Consolidator Grant · 2020

Genetically encoded reporters and sensors for whole animal imaging using photo-modulated Optoacoustics

In vivo imaging of cellular localization and function and visualization of the chemicals that drive life are key challenges for biological research. Current methods limit our insight into this “bigger picture” to either a glimpse (low penetration and small field of view) or a coarse overview (low resolution). Optoacoustic (OA) imaging has the physical means to overcome these limitations, but it lacks the necessary toolbox of genetically encoded reporters and sensors that allow specific probing of localizations and distributions. So far, all efforts to create such a toolbox were impeded by the strong tissue background inherent to OA. Recently, exploiting my longstanding expertise in…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.