Gines Lab

National Centre for Scientific Research (CNRS)

Ile-de-France (FR1) · France

ERC-funded
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Research focus

ERC Starting Grant · 2020

Molecular Programming for MicroRNA profiling

MicroRMicroRNAs, a class of transcript responsible for the fine regulation of gene expression, are emerging as promising biomarkers for cancer monitoring (diagnostic, prognostic and prediction of therapy response. The concentration profiling of – stably present – microRNAs from liquid biopsies represents a hopeful opportunity to fight these diseases, enabling large population screening for early cancer appearance and monitoring in real-time the treatment response. However, current microRNA detection methods do not meet performances in term of sensitivity, multiplexing and practicability to bring microRNA signatures in the front line of clinical applications. The objective of this research…

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