Ding Lab

Leiden University

West-Nederland (NL3) · Netherlands

ERC-funded
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ERC Starting Grant · 2021

Unravelling novel mechanisms of defense gene activation: a gateway to elevate disease resistance in plants

Plant diseases are widespread and constitute a major threat to food production. Understanding the molecular mechanisms by which plants resist pathogens is essential to design better strategies for protecting crops from diseases. Strict regulation of plant defense gene expression plays a critical role in establishing an effective and fine-tuned immune response; their insufficient expression leads to diseases, while their overexpression can result in autoimmunity and severe fitness penalties. My own recent work using systems biology approaches reveals hidden components inferred by defense gene regulatory networks as essential players in plant immunity. The next challenge lies in establishing…

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