ERC Starting Grant · 2021
Engineering vasoactive probes for brain-wide imaging of molecular signaling
Brain function depends on spatiotemporally defined brain-wide signaling via molecules such as neurotransmitters. No current technology can measure signaling molecules throughout the brain with sufficient spatial and temporal resolution in living mammals. This poses a major roadblock for understanding how molecular neuronal communication coordinates whole-brain function. Magnetic resonance imaging (MRI) currently provides the highest brain-wide resolution. Dynamic imaging of blood flow and oxygenation in the finely arborized vasculature, so-called functional MRI (fMRI), is the only method that can visualize whole-brain function in mammals and humans. However, MRI is inherently insensitive,…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.