Einsle Lab

University of Freiburg

- · Germany

ERC-funded
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ERC Advanced Grant · 2023

Harnessing the Catalytic Potential of Nitrogenases

Biological nitrogen fixation is nature’s alternative to the industrial Haber-Bosch process that currently feeds at least half of the human world population through the provision of nitrogen fertilizers. In addition to its high energy demand, the process increasingly leads to various ecological problems, as its annual output steadily grows with demand. Haber-Bosch ammonia synthesis leads to the release of the greenhouse gases CO2 and N2O and to eutrophication of waters and aquifers because a substantial portion of nitrogen is lost to competing chemical and biological processes. One solution for this is to transfer the enzyme directly into food crops. GOFIXIT will establish the recombinant…

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