Sunbul Lab

University of Heidelberg

Baden-Württemberg (DE1) · Germany

ERC-funded
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Research focus

ERC Consolidator Grant · 2023

Decoding subcellular spatial biology with high precision using RNA photocatalysts

RNA is a fundamental component of life. Complex, dynamic, and spatial networks of molecular interactions between RNAs and other biomolecules are essential for maintaining cellular homeostasis. Disruptions in the RNA interactome have been linked to a number of human diseases, implying that these molecular interactions could represent a new family of unexploited therapeutic targets. Despite the growing appreciation of the importance of RNA, discovery, and characterization of RNA interactions at the transcriptome level is lagging behind, mainly due to the limitations of the existing methods including low precision, low throughput, low coverage, biased analysis, complicated protocols involving…

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