Moschou Lab

Foundation for Research and Technology Hellas

Νησιά Αιγαίου, Κρήτη (EL4) · Greece

ERC-funded
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ERC Consolidator Grant · 2023

Limited proteolysis mechanisms in plants for selective protein translation to improve heat tolerance

Heat waves threaten agriculture in the EU and worldwide. Exactly how we can protect our crops precisely and rapidly from heat is a lingering question with important implications for future food security. My aim with PLANTEX is to explore the potential of a rapid stress response that my lab has discovered and incorporate this knowledge into the design of new breeding strategies to improve crops. To bolster heat tolerance, I propose an innovative approach for the control of protein production networks by repurposing proteolytic pathways that control the dynamics of organelle-like assemblies known as condensates. My lab pioneers the study of proteolysis on the formation of condensates with…

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