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ERC Consolidator Grant · 2023

Deep optimized generation for antimicrobial peptide discovery

The DOG-AMP project will develop cutting-edge methods for Deep Optimized Generation (DOG), and use them to transform the emerging field of AntiMicrobial Peptide (AMP) discovery. Continuous overuse of antibiotics fuels the outgrowth and spread of multi-drug resistant microbial strains. Increasing antimicrobial resistance is already now a major health and economic hazard, and is expected to account for 10 million deaths globally per year by 2050, exceeding deaths caused by cancer. AMPs are short peptides that can actively and selectively kill antibiotic-resistant pathogens, and as such are considered the most promising strategy for fighting antimicrobial resistance. Still, intensive research…

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