ERC Starting Grant · 2023
Biosensing by Sequence-based Activity Inference
The ability of cells to sense and respond to signals is an essential requirement of life. Genetically encoded biosensors meet this need by detecting, for example, chemicals and triggering gene expression in response. This concept is used across the life sciences to sense molecules in basic research, diagnostics and treatment. Crucially, biosensors can be used to isolate and engineer microbes that sustainably produce value-added chemicals and thus play a key role in the transition to a circular economy. However, native biosensors are mostly unfit for synthetic applications in terms of molecules and concentrations they respond to. Moreover, little is known about the relationship between…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.