ERC Advanced Grant · 2024
My group’s recent work mapping organ-specific proteome reactivity to reactive lipids (2024 Cell in press) provides a key step toward decoding how cell-specific reactive chemical signaling impacts animal decision-making. This knowledge is biomedically important because understanding spatiotemporal proteome reactivity to innate reactive metabolites is a burgeoning concept relevant to precision drug design. Yet, achieving comprehensive cartography of living systems featuring both locale and function of individual reactive metabolites remains difficult. One metabolite class of emerging significance where such technological voids are deeply felt is mitochondria-derived reactive metabolites…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.