Lampel Lab

Tel Aviv University

- · Israel

ERC-funded
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ERC Starting Grant · 2024

Designer Condensates for Regulation of Catalytic Processes

Living cells have evolved to provide subcellular microenvironments that accommodate and control specific (bio)catalytic processes. These compartments include membrane-bound and membraneless organelles, or biomolecular condensates. New breakthroughs in studying and characterizing cellular biomolecular condensates have facilitated researchers to design synthetic condensates that are formed by liquid-liquid phase separation of engineered proteins, polypeptides, peptides, or nucleic acids. Yet, a precise regulation of designed condensates’ properties and their utilization for nanobiotechnological applications remains a major challenge. I propose to utilize my expertise in peptide design to…

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