ERC Starting Grant · 2025
Effector-Guided Engineering for Crop Resistance
PREDESIGNX aims to revolutionize crop protection strategies by developing a comprehensive pipeline for engineering durable disease resistance in Solanaceous crops. This ambitious project integrates advanced computational predictions, synthetic biology, and translational research to reduce pathogen-caused losses. The project is structured around three interconnected work packages: 1. TARGET: Predict effectors and identify their host targets using advanced computational tools and large-scale genomic data. Validate predictions with high-throughput experimental approaches in planta. 2. BIOENGINEERING: Explore natural domain integrations in well-characterized NLR systems, including Pik and…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.