Marchal Lab

Leibniz Institute of Plant Biochemistry

Sachsen-Anhalt (DEE) · Germany

ERC-funded
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ERC Starting Grant · 2025

Optimised plant immune receptor pairs for improved disease resistance

CooPAIRation is an ambitious project that aims to harness the genetic diversity and evolutionary history of the TaPik wheat immune receptor pair to determine the molecular mechanisms underpinning paired receptor compatibility and guide the design of optimised immune receptor pairs for disease resistance. Bioengineering new resistance profiles in plant immune receptors offers a powerful solution for the timely deployment of new disease resistance traits in the field to fight off rapidly evolving plant pathogens that threaten food security. However, bioengineering plant immune receptor pairs often leads to suboptimal immune responses, likely due to receptor incompatibility caused by the…

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