ERC Starting Grant · 2025
Unravelling bacterial immunity against predatory bacteria: the last line of defence
In times of rising antimicrobial resistance (AMR), natural predators of bacteria have great potential as alternatives. However, as with antibiotics, their efficacy is modulated by the ability of bacterial targets to develop resistance. For bacterial predators this relates specifically to understanding predator-prey interactions and particularly prey defence to attack and early stages of infection. However, in stark contrast to phage defence systems, little is known about bacterial prey resistance to predatory bacteria, and barely anything about prey bacterial immunity against predatory bacteria which is the last line of prey defence in the periplasm or cytosol. While the factors determining…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.