Russell Lab

Academic Medical Center of the University of Amsterdam

West-Nederland (NL3) · Netherlands

ERC-funded
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ERC Consolidator Grant · 2018

Navigating the evolutionary routes of influenza viruses

Seasonal influenza viruses re-infect us repeatedly, escaping antibody recognition, due to the evolution of the virus itself. Being able to predict when and how the virus will evolve would be transformative for influenza virus control. Problematically, we have only observed one of the likely many possible routes of virus evolution. We do not know how many viable routes may have existed or about the repeatability of the observed evolution. These knowledge gaps limit the predictability of influenza virus evolution. NaviFlu will fill these gaps by rigorously assessing the repeatability of influenza virus evolution and the diversity of routes the virus can explore. Recent work has shown that…

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