ERC Consolidator Grant · 2019
Evolution of gut-associated microbial communities and its functional relevance in health and disease
The gut is a highly dynamic microbial ecosystem that controls human health through its collective metabolic activities. Microbial communities form metabolic networks that are essential for dietary breakdown, production of bioactive metabolites and resistance to infections. Bacterial lineages making up these networks evolve rapidly to adapt to the microbial, metabolic and immune environment of the gut. The lack of suitable model systems has limited our current understanding of the relevance of microbial community evolution in the gut and its impact on microbe-host mutualism. EvoGutHealth aims to fill this gap in knowledge by using an innovative, tuneable oligo-microbial model system that…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.