Pilhofer Lab

Research focus

ERC Consolidator Grant · 2020

Cryo-electron tomography for microbial ecology and evolution

The cryo-electron microscopy (cryoEM) modalities of single particle analysis and cryo-electron tomography (cryoET) have revolutionized the fields of structural biology and cellular biochemistry, and they enabled groundbreaking insights into primarily hypothesis-driven, mechanistic problems, using well-established model systems. High-throughput sequencing technologies have revolutionized microbial community studies and changed our view of the diversity of life. In order to understand how microbes function and interact with other cells, however, sequencing- and cultivation-based techniques must be complemented with experiments that elucidate phenotypes in situ at the single-cell level. In Aim…

From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.