Spang Lab

Netherlands Foundation of Scientific Research Institutes

West-Nederland (NL3) · Netherlands

ERC-funded
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ERC Starting Grant · 2020

A multilevel approach to address the role of Archaeal Symbionts in the Evolution of Life

Microbial symbioses play an essential role in most aspects of life’s evolution and enabled major evolutionary events such as the origin of eukaryotes. But in spite of the importance of symbioses, our knowledge is based on a limited number of microbial host-symbiont systems, few of which include Archaea. Notably, recent cultivation-independent approaches have revealed two hugely diverse microbial groups of putative deep-branching archaeal and bacterial symbionts referred to as DPANN and CPR, respectively. The major aims of ASymbEL are to test the hypotheses that (a) DPANN, together with CPR, have key positions in the tree of life, requiring to revise our view on the early evolution of cells…

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