ERC Advanced Grant · 2021
Primate X chromosomes evolve extraordinary fast and are also tightly associated with the establishment of reproductive barriers between emerging species. The hypothesis of this proposal is that genetic conflicts between the X chromosome and the rest of the genome during spermatogenesis cause rapid X chromosome evolution and build reproductive barriers. Genetic conflicts for transmission to haploid gametes, called meiotic drive, will cause non-adaptive evolution, which is expected to be countered by other genomic elements that will then be under selection. Such an arms race is expected to lead to a very rapid evolution of the X chromosome and a fast accumulation of incompatibilities between…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.