Moissl-Eichinger Lab

Medical University of Graz

Südösterreich (AT2) · Austria

ERC-funded
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ERC Advanced Grant · 2024

Archaeal keystone species in host microbiomes: Understanding and controlling Methanobrevibacter for Environmental and Health Benefits

Archaea, the most ancient domain of life, play a crucial yet largely underappreciated role in human microbiomes and Earth's nutrient cycles. Among them, Methanobrevibacter species are particularly important for methane production in ruminants, accounting for up to 6% of anthropogenic greenhouse gas emissions and are prevalent in animal and plant microbiomes. In recent years, I have become intrigued by the impact of Methanobrevibacter on human physiology. Our research has shown that two distinct Methanobrevibacter species influence the availability of essential vitamins and metabolites by shaping the entire gut microbiome. Despite their recognized importance for health, our mechanistic…

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