Sachdeva Lab

University of Vienna

Ostösterreich (AT1) · Austria

ERC-funded
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Research focus

ERC Consolidator Grant · 2024

Polygenic Adaptation across Space

Rapid advances in sequencing are making an unprecedented amount of genomic data available from diverse organisms. However, theoretical and statistical frameworks for analysing sequences lag far behind, yet are crucial for identifying functionally important regions of the genome and predicting their contributions to key traits, e.g., disease risk in humans, yield in crops and environmental maladaptation in endangered populations. While numerous tools of genomic prediction, notably Genome-Wide Association Studies (GWAS), have been developed in recent years, a common and unsolved challenge is to disentangle the effects of different evolutionary processes on genomic variation. In particular,…

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