ERC Consolidator Grant · 2024
Evolutionary Arms Races Shaping the Germline Epigenome
Germline chromatin pathways are key to the stable inheritance of genetic and epigenetic information. They also participate in intense evolutionary battles between genetic entities with opposite incentives during reproduction. These include conflicts between transposons and host genomes, between chromosomes during meiosis, and between maternal and paternal epigenomes. Such genetic conflicts are predicted to drive evolutionary arms races leading to rapid genetic and epigenetic innovations. Contrary to current dogmas focusing on conserved features, my research program explicitly tackles the functional consequences of epigenome rapid evolution during mammalian reproduction and disease,…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.
← All labs at National Institute of Health and Medical Research (INSERM)