Berasategui Lab

Free University and Medical Center Amsterdam (VU-VUmc)

West-Nederland (NL3) · Netherlands

ERC-funded
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ERC Starting Grant · 2024

Cross-kingdom symbionts: plant pathogens as insect mutualists.

By vectoring plant pathogens, herbivorous insects are key determinants in the epidemiology of numerous plant blights. For a vector-borne phytopathogen, natural selection favors upgrading insect fitness to enhance transmission to an uninfected plant. It is currently unclear how a microbe balances this dual symbiotic lifestyle, featuring markedly different interaction outcomes: as a plant pathogen and an insect mutualist. Likewise, little is known about the molecular mechanisms underlying pathogen specificity, and the genomic basis and consequences of cross-kingdom host shifts along the parasitism-to-mutualism continuum. I will tackle these questions using an emergent model system: the…

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