Welte Lab

Radboud University Nijmegen

Oost-Nederland (NL2) · Netherlands

ERC-funded
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ERC Consolidator Grant · 2025

Uncovering novel metabolism, microbial interactions and environmental roles of electroactive ANaerobic MEthanotrophic archaea

Anaerobic methanotrophic (ANME) archaea are ecologically critical microorganisms that remove methane from natural environments, thereby reducing emissions of this potent greenhouse gas. However, their physiology and ecology remain vastly unexplored due to the lack of axenic (single species) cultures of ANME archaea, their slow doubling times (in the order of weeks or months) and their complex nutritional requirements and interactions with other organisms. Recently, we achieved a breakthrough in ANME archaea cultivation, developing bioelectrochemical systems with highly enriched (>95% pure) and rapidly growing (doubling time ~4.5 days) cultures of Ca. Methanoperedens, a representative…

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