ERC Starting Grant · 2016
Epilepsy Controlled with Electronic Neurotransmitter Delivery
Many efficient drugs have been designed to treat neurological disorders, but have failed in the clinic because they were toxic, could not cross the blood-brain barrier, and/or had deleterious side effects in healthy regions. I propose a conceptual breakthrough to solve these three issues, with minimally-invasive organic electronic ion pumps (OEIPs) to provide targeted treatment where and when it is needed. I will use epilepsy as the disease model because of its high rate of drug-resistance (30%) and will offer concrete opportunities for clinical transfer of such state-of-the-art technology. The clinical problem: Resective surgery is frequently the last option available to a patient with…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.