ERC Consolidator Grant · 2017
Targeting Meniscus Degradation in Osteoarthritis
My goal is to determine the molecular degradation of meniscus tissue, a “new” disease that leads to degenerative meniscus tears and osteoarthritis (OA). My prior research has revealed that meniscus tears are a frequent entity in OA, not typically caused by knee trauma. By focusing on the meniscus, we aim to discover novel biomarkers and new targets for pharmaceutical intervention against OA, by preventing meniscus degradation and stimulating its regeneration. In our ageing population, the burden of OA is rapidly increasing, making the first disease-modifying OA treatment an urgent matter. The proposal is based on my biobank consisting of human tissue from total knee joint replacements, knee…
From the public funding record at EU CORDIS. Describes the funded project, not the reviews below.