Melen Lab

Karolinska Institute

Östra Sverige (SE1) · Sweden

ERC-funded
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Research focus

ERC Starting Grant · 2017

A TRranslational approach to Identify Biomarkers for Asthma and Lung function impairment

Asthma is a chronic inflammatory disease of the airways that cause symptoms like wheezing and breathlessness. In children, asthma is the most common chronic disease and according to the WHO, more than 300 million people are affected globally. There is no curative treatment available. Persistence of childhood asthma into adult life is associated with lung function impairment and increased risk of chronic obstructive pulmonary disease, COPD. Evidence is now emerging that adult diseases, like COPD, may have their origin early in life. However, there are no established biomarkers that can accurately monitor asthma progression or predict development of COPD in adults. In this TRIBAL project, I…

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